Bisphosphonates are the most widely used medicines in osteoporosis and effect by reducing the bone resorption. However, the long term effects of this medicine are not known exactly. In the literature, subtrochanteric diaphysis stress and failure fractures have been defined associated with long term bisphosphonate use. A case is presented here who has been receiving alendronate treatment for 10 years and who has developed multipl fractures (femoral diaphysis, pubic ramus, sacrum) with spontaneously or low energy trauma.