Turkish Journal of Physical Medicine and Rehabilitation 2001 , Vol 47 , Num 1
Fizik Tedavi Uygulanan Gonartroz Hastalarında Asemetasin Eklenmesinin Etkinliğini Araştıran Çift Kör, Plasebo Kontrollü Çalışma
Nil ÇAĞLAR 1 ,Berrin Gündüz 2 ,Kadriye ÖNEŞ 1 ,Meltem Esenyel 3 ,Aynur Şahin 4 ,Erhan Kefman 5
1 Clinic of Physical Medicine and Rehabilitation, İstanbul Physical Medicine and Rehabilitation Training and Research Hospital, İstanbul, Turkey
2 İstanbul Fiziksel Tedavi Rehabilitasyon Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, İstanbul, Türkiye
3 SSK Vakıf Gureba Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, İstanbul
4 Vakıf Gureba Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul
5 Vakıf Gureba Eğitim ve Araştırma Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul

Gonarthrosis who are Receiving Physical Therapy; a Placebo Controlled, Double-Blind Trial. The aim of this study was to investigate the effects of adding a non-steroidal  antiinflamatory drug, acemetacin to patients with gonarthrosis who are receiving physical therapy, on patients’ pain,  physical and laboratory findings and record the side effects of the drug. 32 patients with gonarthrosis were included in this study. Among the physical the-rapy modalities hot-pack, ultrasound and transcutaneal electrical nerve stimulation were applied to all patients. The patients were randomly divided into two groups. The first group were given 120mg of acemetacin daily while the second group recieved placebo capsules of acemetacin  twice a day. The two groups  were followed for 21 days for the parameters of pain at rest, pain with movement, pain with pressure, limitation in range of motion, joint  circumference, the evaluation of treatment efficacy by both patient and physician, side effects and laboratory tests. The results of the two groups were compared. As a result, on the 7th day there was a significant improvement in pain at rest and  pain with movement in only the acemetacin group. There was no significant difference in any of the  other parameters between the two groups.

Keywords : Acemetacin, gonarthrosis, physical therapy