Turkish Journal of Physical Medicine and Rehabilitation 2008 , Vol 54 , Num 2
Assessment of Trabecular Bone Structure with Magnetic Resonance T2 Relaxation Time in Osteoporosis
Yeşim Akyol 1 ,Gamze Alaylı 2 ,Barış Diren 3 ,Kıvanç Cengiz 4 ,Ferhan Cantürk 2
1 Department of Physical Medicine and Rehabilitation, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey
2 Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Samsun, Türkiye
3 Ondokuz Mayıs Üniversitesi Tıp Fakültesi Radyoloji Anabilim Dalı, Samsu
4 Ondokuz Mayıs Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Samsu

Objective: This study was planned to investigate the utility of Magnetic Resonance Imaging MRI in assessing osteoporosis in a quantitative manner by evaluating bone micro architecture and to assess the correlation between MRI measurements and dual energy X-ray absorptiometry (DXA). 
 

Materials and Methods: The study group consisted of 31 postmenopausal osteoporotic women and control group consisted of 31 healthy postmenopausal women with normal bone mineral density (BMD). BMD measurements were performed with DXA at spine and at femur. The MRI T2 relaxation time (T2 RT) measurements were performed at lumbar 3 (L3) vertebra and calcaneus. The results of L3 vertebra DXA measurements of the postmenopausal subjects were compared with L3 vertebra MRI T2 RT and calcaneus T2 RT.
 

Results: There was a significant difference between postmenopausal women with normal BMD and those with low BMD regarding the T2 RT of L3 vertebra and calcaneus (p<0.001). We found a negative correlation between L3 vertebra BMD and L3 vertebra T2 RT and calcaneal T2 RT. There was a positive correlation between L3 vertebra T2 RT and calcaneal T2 RT.
 

Conclusion: The MRI results obtained by this technique were found to be correlated with the DXA results. It seems to be possible to discriminate postmenopausal osteoporotic and healthy women with MR T2 RT which assess trabecular bone structure.

Keywords : Osteoporosis, MRI T2 relaxation time, dual energy x-ray Absorptiometryp