Turkish Journal of Physical Medicine and Rehabilitation 2016 , Vol 62 , Num 3

A case of familial Mediterranean fever carrier and intermittent hydrarthrosis resistant to colchicine, arthroscopic synovectomy, radioactive synovectomy and repeated joint injections

Ayhan Esmer 1 ,Fikriye Figen Ayhan 1 ,Hakan Özsoy 2 ,Pınar Borman 1 ,Aynur Karagöz 1
1 Ankara Eğitim ve Araştırma Hastanesi Fiziksel Tıp ve Rehabilitasyon Kliniği, Ankara, Türkiye
2 Ankara Eğitim ve Araştırma Hastanesi Ortopedi ve Travmatoloji Kliniği, Ankara, Türkiye
DOI : 10.5606/tftrd.2016.27880 Intermittent hydrarthrosis is an uncommon situation, usually seen in major joints, most frequently in knee, with episodic synovitis attacks. It can be treated with low dose colchicine, non-steroid anti-inflammatory drugs, gold salts, intra-articular steroids and synovectomy. In this article, we presented a 32-year-old patient with intermittent hydrarthrosis and carrier of familial Mediterranean fever resistant to arthroscopic synovectomy, radioactive synovectomy, repeated joint injections, colchicine, and non-steroid anti-inflammatory drugs. His symptoms of intermittent hydrathtrosis could be controlled by step-up combined disease modifying antirheumatic drug treatment hydroxychloroquine plus methotrexate in addition to colchicine. Keywords : Colchicine; familial Mediterranean fever; hydrathtrosis; hydroxychloroquine; intermittent; methotrexate