Turkish Journal of Physical Medicine and Rehabilitation 2008 , Vol 54 , Num 2

Monostotic Paget Disease of Bone or Bone Metastasis?

Nesrin Demirsoy 1 ,Jale Meray 2 ,Özlem Erdem Süer 3 ,Zelal Keleş 2
1 Department of Physical Medicine and Rehabilitation, Gazi University Faculty of Medicine, Ankara, Turkey
2 Gazi Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Ankara, Türkiye
3 Gazi Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Ankara

Paget’s disease of bone is a metabolic bone disorder with male predominance and characterized by increased bone turnover. Recent literature indicates a reduction in incidence and severity. We report a 55 years old female patient who was admitted with knee pain, and whose pelvis x-ray demonstrated pathological features. She was investigated with preliminary diagnoses of Paget’s disease of bone, osteosclerotic bone metastasis and primary bone tumor. Histopathological examination of bone biopsy confirmed Paget’s disease of bone and Paget’s disease of bone is reviewed. 

Keywords : Paget’s disease of bone, metastatic bone disease